The FLT3-mutated AML cell lines MV4-11 and MOLM-13 as well as FLT3 wildtype cell lines OCI-AML3, OCI-AML5, IMS-M2 and HL60 were treated with low concentrations of sunitinib, PF-04691502, GANT61 or the triple combination. This evidence concerns the gene FLT3 and acute myeloid leukemia.