WFDC2 and neoplasm: The logistic regression analysis, which we performed to find the efficacy of CA 125 and HE4 in differentiating groups with malignant and benign adnexal masses, the CA 125 tumour marker was statistically insignificant in differentiating between benign and malignant adnexal masses (p=0.491), whereas HE4 was found to be statistically significant in this differentiation (p=0.025).