PAPPA and Large for gestational age: Additionally we found some associations between PAPP-A, fβ-hCG and adverse outcomes such as: PAPP-A <1st percentile and fβ-hCG >95th percentile is associated with adverse pregnancy outcome (p=0.038 and p=0.034, respectively); fβ-hCG >95th percentile is associated with fetal macrosomia (p<0.01).