TP53 and neoplasm: RT-qPCR analysis was applied to detect the expression of apoptosis-related cysteine peptidase-9 (caspase9), apoptosis-related cysteine peptidase-3 (caspase3), Tumor suppressor 53 (TP53), ATP-binding cassette sub-family G-2 (ABCG2) and Multidrug resistance-1 (MDR1) in the tumor sections treated with PTX-loaded NPs in comparison with free PTX (Figure 6).