Probably, the involvement of ZnT3 in the regulation of synaptic Zn2+ levels is at the very heart of previously described changes in the expression of this zinc transporter during various pathological processes in the brain, including ischemia Huntington’s, Alzheimer’s and Parkinson’s diseases, epilepsy and mechanical damage (Devirgiliis et al. 2007; Chi et al. 2008; Whitfield et al. 2015). Here, SLC30A3 is linked to Parkinson disease.