KDM3A and Familial prostate cancer: In detail, putative KDM3A-regulated genes included pathways involved in androgen response, androgen receptor signaling, androgen biosynthesis, prostate cancer, pathways in cancer, cholesterol homeostasis, bile acid metabolism, aldosterone-regulated reabsorption, and progesterone regulation, hinting at the possibility of hormone nuclear steroid receptor involvement (enrichment with p-values below 2.62E-02 and q-values below 9.35E-02 correcting for multiple hypotheses testing) (Table 2).