KDM3A and neoplasm: KDM3A (lysine demethylase 3A; Gene ID: 55818; also referred to as JMJD1A or JHDM2A) is crucial for gene regulation in a variety of biological activities such as spermatogenesis, metabolism, stem cell activity and tumor progression by demethylating mono- or di-methylated H3K9 [3–5].