NOMO1 and colorectal carcinoma: One of the genes located in 16p13.12-p13.11 is NOMO1. Unexpectedly, we found NOMO1 deletion not only in cases with cytogenetic deletion in 16p, mainly in the EOCRC, but also in most early-onset cases without 16p deletion (34 out of 34 EOCRC cases studied by aCGH and FISH), while it barely reached 12% in the late-onset CRC subset.