NOMO1 and colorectal carcinoma: Taken together, from a total of 75 EOCRC cases we found 61 patients (81.3%) with a homozygous loss; 7 patients (9.3%) with a heterozygous loss; and 7 patients (9.3%) without loss of NOMO1. Of the other 50 late-onset CRC added, only one showed NOMO1 homozygous deletion, 4 showed heterozygous deletion, and 45 showed NOMO1 wild-type.