GJA1 and hepatitis A virus infection: This is consistent with previous reports of NPNT expression in hepatitis, inducing the development of granuloma-like cell clusters of hepatocytes.37 Cardiomyocytes grown on NPNT not only exhibited increased adhesion but also expressed high amounts of connexin-43 along their intercellular junctions, indicating well-established intercellular communication, and couple electrically with each other resulting in synchronous beating.31