TIAM1 and colorectal carcinoma: To determine the association between TIAM1 expression and overall survival, we grouped nuclear TIAM1 staining into low (scores 0–1) or high (scores 2–3) categories and found that patients having CRC with high nuclear TIAM1 had significantly better survival than patients having CRC with low nuclear TIAM1 (Figures 1C and S1C).