Recent studies have confirmed severe parotid involvement, purpura, leukopenia, anti-La antibodies, raised levels of BAFF and beta2-microglobulin, cryoglobulins, monoclonal band, and hypocomplementemia as risk factors for B-cell lymphoma [24, 25, 29, 30]. The gene discussed is TNFSF13B; the disease is Decreased total leukocyte count.