For B-cell non-MALT lymphomas, the prognostic factors included anemia (HR 2.58; p = 0.047), monoclonal gammopathy (HR 3.45; p = 0.024), cryoglobulins (HR 3.34; p = 0.028), and low C4 levels (HR 3.83; p = 0.014). Here, C4A is linked to monoclonal gammopathy.