Accumulative evidence reveals that in addition to its innate glycolytic functions, ENO1 plays important role in several biological and pathophysiological process; functioning as plasminogen receptor, playing role in myogenesis and muscle regeneration as well as in cell apoptosis etc [21], Higher expression of ENO1 is correlated with several kinds of cancer development [11, 12, 14, 22, 23]. Here, ENO1 is linked to cancer.