Previously several CAD related variants and environmental factors were reported, such as type 2 diabetes mellitus (T2DM), dyslipidemia, hypertension and genetic factors, including proliferator-activator receptor-G (PPAR-G) and Cytochrome P450 (CYP) family, are significant risk factors for CAD [5–7]. Here, PPIG is linked to type 2 diabetes mellitus.