Based on these facts, we performed targeted phospholipidomic profiling of LNCaP prostate cancer cells after ECI2 knockdown, which revealed accumulation of all major classes of phospholipids, phosphatidylserine (PS), phosphatidylcholine (PC), phosphatidylethanolamine (PE) and phosphatidylinositol (PI) (Figure 3E and Supplementary Figure 2). Here, ECI2 is linked to Familial prostate cancer.