Knockdown of GAS5 in A375 cell line facilitated wound healing in a wound healing assay and increased the proteolytic potential.[80] GAS5 administered to nude mice significantly inhibited tumor growth of GAS5 expressing melanoma cells.[80, 93–95] Further research is awaited to explore if enhancing GAS5 in melanoma cells could have therapeutic value. The gene discussed is GAS5; the disease is neoplasm.