UCA1 and cancer: Urothelial carcinoma associated 1 (UCA1) was originally detected in bladder transitional cell carcinoma where it is believed to promote invasion and cancer progression.[61] In melanoma, UCA1 was found to be upregulated in both primary and metastatic melanoma samples.[62, 63] UCA1 is believed to exert its oncogenic functions by acting as a miRNA sponge for miR-507.