The two chimeric modules were complemented by an immunohistochemical analysis which, in addition to ZEB1 and SLUG, included E-cadherin as a marker of an epithelial/MErT phenotype that is acknowledged to have important pluripotency and reprogramming functions [20], desmin as a marker of a mesenchymal/EMT phenotype, and P-cadherin, a recently proposed marker of hybrid/partial EMT and cancer stem cells (CSCs) [21]. This evidence concerns the gene ZEB1 and cancer.