Intriguingly, after the finding of a positive correlation between PDGFRA tumor cell expression and stroma desmoplasia in a first study based on an in vitro analysis and IHC and ISH investigations of histological sections [42], a second and more recent IHC study has found that PDGFRA inversely correlates with tumor- associated desmoplasia [44]. This evidence concerns the gene PDGFRA and neoplasm.