The altered lncRNA expression profile possessed a total of 9 individuals, yet 7 of them (TUG1, 91H, HULC, BANCR, FGFR3-AS1, HOTTIP, and OMRUL) were overexpressed in osteosarcoma tissues/plasma, and 2 (MEG3 and TUSC7) were down-regulated. This evidence concerns the gene HULC and osteosarcoma.