HULC and neoplasm: Among the altered lncRNA profiles, 7 lncRNAs involved TUG1, 91H, HULC, BANCR, FGFR3-AS1, HOTTIP and OMRUL [14, 16–19, 21–23], were notably increased in patients with osteosarcoma and strongly correlated to worse clinical outcomes, indicating that such lncRNAs may play oncogenic roles in maintaining tumor progression.