ERBB2 and ovarian carcinoma: In addition, HOTAIR was found to control the expression of Rab22a by sponging miR-373 in ovarian cancer [15]; Liu et al., showed that HOTAIR functions as a competing endogenous RNA to regulated human epidermal growth factor receptor 2 (HER2) expression by sponging miR-331-3p in gastric cancer [16].