Through genotyping of three tag missense variants on BRCA1/2 in 603 Chinese pancreatic cancer patients, we discovered the prognostic value of rs1799966 (c.4837A>G [p.Ser1613Gly]) on BRCA1. Further stratification analyses showed that the association was particularly in patients with local advanced stage, but not patients in local or metastatic stage. The gene discussed is BRCA1; the disease is pancreatic neoplasm.