CSRP2 and acute lymphoblastic leukemia: To study the biological role of CSRP2 in B-cell ALL we developed 2 B-cell lines: (1) BV173 in which CSRP2 was stably knocked-down (CSRP2-KD); and (2) a CSRP2-overexpressing Ramos cell line (CSRP2-OE; Figure 5A).