Accuracies of combinations of antibodies revealed that the combined IgG responses to Tpx and TB-LTBI and IgA response to MPT64 best discriminated active TB from ORD with a positive predictive value of 0.95 (95% CI; 0.74-0.99) and negative predictive value of 0.97 (95% CI; 0.85-0.99). This evidence concerns the gene TPO and tuberculosis.