In our analysis, only Notch 1 mRNA high expression was significantly associated with poor PFS in TP53 wild type ovarian cancer patients, HR 1.86 (1.05–3.31), p = 0.031, but Notch 1 mRNA high expression was significantly associated with favorite PFS in TP53 mutation type ovarian cancer patients, HR 0.78 (0.6–0.99), p = 0.045. The gene discussed is TP53; the disease is ovarian cancer.