For example, Wang Y demonstrated that lncRNA LINC00161 could bind miR-645, which was reported to target IFIT2, and regulated IFIT2 expression via miR-645; and LINC00161 sensitized osteosarcoma cells to cisplatin-induced apoptosis through regulation of the miR-645-IFIT2 axis [33]. This evidence concerns the gene IFIT2 and osteosarcoma.