S100A8 and peptic ulcer disease: However, despite the increase in the number of cases associated with H. pylori, there are few data on the prevalence of this infection in some gastroduodenal diseases, and still fewer on the distribution of the vacA, cagA or vacA/cagA genotypes in patients with peptic ulcers, non-ulcer dyspepsia or gastric cancer [6, 10, 11, 27, 42–45], while there is only one study on the frequency of the vacA, cagA and babA2 genotypes in patients with chronic gastritis [10].