Finally, we observed six significantly enriched EVI-1/RUNX (also called AML) gene sets uniquely regulated in cells expressing KR-PR (+SPRMs) relative to cells expressing WT-PR (+SPRMs) (Additional file 3F), suggesting that phosphorylated PRs and RUNX factors may cooperate on selected target genes. The gene discussed is PGR; the disease is acute myeloid leukemia.