Given that one of the hallmarks of cancer is avoidance of apoptosis [5, 10], and that the mode of action of the tested peptides involves apoptosis induction (Figures 2G, 4A and Supplementary Figure 2B, 2C), the expression levels of apoptosis-related proteins in PBS/DMSO- and Tf-D-LP4-TTs were analyzed (Figure 4B–4D). This evidence concerns the gene TF and cancer.