GBM patient-derived cell lines, such as U-87MG (mutated PTEN), CRL-2610 (LN-18) (mutated PTEN and p53), U-251MG (mutated PTEN and p53) and U-118MG (mutated PTEN and p53), showed high expression of TfR (Figure 1C). The gene discussed is PTEN; the disease is glioblastoma.