To assess the direct binding between MALAT1 and PRC-related pathway markers, an RNA immunoprecipitation study was performed using the T cell lymphoma cell line, which shows high endogenous expression of PRC-related markers; this assay confirmed the direct binding of MALAT1 to EZH2, SUZ12, and H3K27me3. The gene discussed is MALAT1; the disease is T-cell non-Hodgkin lymphoma.