MME and posterior cortical atrophy: De-regulated expression of the proteins MME, TFRC, XRCC6, TOP2A and CD59 were found to be significantly associated with increased risk of PCa recurrence in the Galsky-Oh study and also identified as significantly changed in expression between androgen sensitive and androgen independent cell lines (MME, TFRC, XRCC6 and TOP2A) and as result of hypoxia (CD59).