CYSLTR1 and polyp of colon: The AOM/DSS Cysltr1−/− mice mainly exhibited colonic polyps of <1 mm in diameter with no polyps exceeding 1.5 mm, while the wild-type (Cysltr1+/+) counterparts exhibited all sizes of polyps, including polyps exceeding 1.5 mm in size (Figure 1H and 1I).