VARS1 and chronic kidney disease: Four SNPs (rs707926 of VARS, rs76974938 of C21orf59, rs112311672 of HDAC10, rs41272317 of ACAD11) were related (P < 0.05 in at least one genetic model) to CKD, although there was no SNP significantly [P < 2.55 × 10−4 (0.05/196)] associated with this condition (Table 5).