In addition, rs115445569 [C/T (R64Q)] of ACOT11, rs116911833 [G/A (T80M)] of TRIM7, and rs60854092 [T/A (F1689I) of NOTCH2 were related to hyperuricemia, although the genotypes of these SNPs were not related to the serum concentration of uric acid. The gene discussed is NOTCH2; the disease is hyperuricemia.