In order to determine the dynamics of replication of Rac-H strain in primary murine neurons, the copy number of viral DNA released to cell culture medium was examined starting from 24 h p.i. The results showed that the levels of viral DNA released to cell culture medium during long-term infection of neurons with Rac-H strain remained comparatively constant starting from 24 h p.i. (from 1.41 ± 1.09 × 104 in 24 h p.i. to 2.24 ± 0.92 × 104 in 21 days p.i.; P ≤ 0.05). The gene discussed is AKT1; the disease is infection.