Thus, ABCB1 is an important target for adjuvant cancer therapy, such that specific inhibitors could potentially increase intracellular concentrations of cotreated chemotherapies; third generation ABCB1 inhibitors, developed in part using the biophysical structure of ABCB1 as a template for small molecule discovery, have shown efficacy towards tumorigenesis [7, 10]. Here, ABCB1 is linked to cancer.