Quantitative Western blot analysis have revealed increased expression of gp91phox both in the cortex (p = 0.0046) and in the hippocampus (p = 0.0003) and decreased expression in thalamus (p = 0.0035) and caudate nuclei (p = 0.0494) of MD group compared to control group (Figures 1(a) and 1(b)). The gene discussed is CYBB; the disease is Menkes disease.