Strain C18 was identified as sequence type 398 (ST398), clonal complex 398 (CC398), spa type t242, SCCmec type V, and as a carrier of eta, seg, sei, and icaD. Strain C80 was classified as ST5, CC5, t002, SCCmec Iva, and as a carrier of seg, sei, and icaD. Invasive infection by CC398 rarely occurs (3), but strain CC5 belongs to a clonal group known to be involved in a global pandemic caused by MRSA (4). Here, DFFA is linked to infection.