Analysis of MEG3 promoter methylation revealed no significant differences in 19 CpG units between the AML and control groups: MEG3_1_CpG_1, MEG3_1_CpG_3.4, MEG3_1_CpG_15, MEG3_2_CpG_2, MEG3_2_CpG_6, MEG3_2_CpG_10, MEG3_3_CpG_4, MEG3_3_CpG_5, MEG3_3_CpG_11, MEG3_4_CpG_9, MEG3_5_CpG_5.6, MEG3_5_CpG_10, MEG3_7_CpG_6, MEG3_7_CpG_7, MEG3_7_CpG_12, MEG3_8_CpG_7, MEG3_8_CpG_9, MEG3_8_CpG_11, and MEG3_8_CpG_13 (Figure 1). The gene discussed is MEG3; the disease is acute myeloid leukemia.