BTG3 overexpression inhibited the migration and invasion of CRC cells according to wound healing (Figure 2E, p<0.05) and transwell chamber assays (Figure 2F, p<0.05), but induced senescence and differentiation, evidenced by β-galactosidase staining (Figure 2G) and alkaline phosphatase (ALP) activity (Figure 2H, p<0.05) respectively. This evidence concerns the gene BTG3 and colorectal carcinoma.