When the nine parameters were included in the Cox multivariate analysis, PAK4 and lymph node status stood out as independent prognostic factors with regard to both DFS (HR = 2.9, p = 0.011; HR = 3.1, p = 0.000 respectively, Table 2) and OS (HR = 3.713, p = 0.009; HR = 2.385, p = 0.017, respectively, Table 3), and tumor size was an independent prognostic factor with regard to DFS (HR = 0.116, p = 0.035, Table 2). The gene discussed is PAK4; the disease is neoplasm.