The OR for RA per SE copy was 2.61 (95% CI: 1.36, 5.01; P = 3.9 × 10 −3) in all RA cases, and 3.35 (95% CI: 1.64, 6.91; P = 1.0 × 10 −3) in ACPA-positive cases. The gene discussed is PRTN3; the disease is rheumatoid arthritis.