All selected apoptosis-related genes from our microarray analysis, were confirmed to be differentially expressed in TCRγδ+ T-LGL leukemia cases when compared to healthy controls; XIAP, CASP1, BCLAF1 were all validated to be over two-fold higher, and especially CFLAR to an even higher extent than observed in the microarrays (Fig 3). The gene discussed is CASP1; the disease is T-cell large granular lymphocyte leukemia.