CDKAL1 and type 2 diabetes mellitus: We then evaluated whether genetic polymorphisms of CDKAL1 (rs9465871), JMJD1C (rs10761745), and KCNQ1 (rs163177) and iron interacted in the development of T2D, where the minor alleles of CDKAL1 and JMJD1C were used as references to calculate HR (Table 3).