Although the function of JMJD1C is unclear until now, of four genes, JMJD1C may be the most plausible candidate gene as a type 2 diabetes susceptibility gene, because previous studies have reported that JMJD1C may be associated with serum sex hormone-binding globulin (SHBG) levels and serum androgen levels [42, 43] that may influence pathogenesis of type 2 diabetes [44]. Here, SHBG is linked to type 2 diabetes mellitus.