C/EBP-β, as a transcription factor, was reported to positively regulate the expression level of TRIB1.21 To address whether the overexpression of TRIB1 is related to C/EBP-β, we first detected the expression level of C/EBP-β in CDDP-treated and -untreated NSCLC cell lines. This evidence concerns the gene TRIB1 and non-small cell lung carcinoma.