BCL2 and viral infectious disease: For example, US3 PK is involved in the egress of nucleocapsids,114 the maturation of virions,21, 115 enhancing viral spread,116 rearranging the actin cytoskeleton117 and evading antiviral responses.118US3 PK can block apoptosis induced by viral infection, the overexpression of Bcl-2 family proteins, cytochrome C release and Fas/UV-mediated apoptosis.119, 120, 121, 122, 123