We argue that a restricted set of candidate MP proteins, galectin-3-binding protein (G3BP) in particular, could prove highly useful as biomarkers and tools to understanding the role of MPs in the systemic autoimmune disease, systemic lupus erythematosus (SLE), and venous thromboembolism (VTE), and potentially also in cancer and chronic viral infections [8, 11–15]. The gene discussed is LGALS3BP; the disease is systemic lupus erythematosus.