TLR7 and systemic lupus erythematosus: In this study, we used TLR7-deficient (Tlr7−/−) mice and atherogenic diet-fed Apoe−/− mice to test whether TLR7 deficiency affects atherogenesis differently from Apoe−/− mice not on an atherogenic diet or mice on a Faslgld/gld lupus background.