Some combinations of the inflammatory response parameters (eg. lymphocytes, neutrophils, platelets and acute-phase proteins, which are simple and easy to measure using standardized and widely used assays) including platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR) and albumin/globulin ratio (AGR), have been performed to evaluate the prognosis in various cancers, including CRC, and so on [27, 33, 46–48]. The gene discussed is ALB; the disease is cancer.