We found the total mRNA levels of EGFR and four EGFR transcripts were dramatically reduced after PTBP1 stable knockdown (Figure 4B and Supplementary Figure 5), which in agreement with previous study that PTBP1 stablized mRNA of EGFR by inhibiting ANXA7-mediated EGFR degradation in glioblastoma [38]. This evidence concerns the gene ANXA7 and glioblastoma.