Interestingly, we found opposite trends in these two breast tumor subgroups: while PR up-regulated tumors displayed a significant negative correlation between miR-26b and PR mRNA expression fold changes (Figure 5C), a marginally significant negative correlation between miR-23a and PR mRNA expression fold changes (Figure 5B), and weak and insignificant negative correlation between miR-181a and PR mRNA expression fold changes (Figure 5A), PR expression fold changes correlated negatively only with miR-181a expression fold changes (marginally significant) in PR down-regulated tumors (Figure 5A). Here, PGR is linked to breast neoplasm.