FUCA1 and Ehlers-Danlos syndrome, musculocontractural type: Since we [34] and others [35, 36] reported that FUCA-1 is a target of p53 and since the majority of ATCs were reported to harbor p53 mutations [37], it is highly probable that the lower expression of FUCA-1 in ATCs is related to alterations of the p53 gene.