NUSAP1 and Familial prostate cancer: In several diverse datasets, increased NUSAP1 expression is associated with recurrence after radical prostatectomy [11], and it is found in prognostic gene sets associated with high grade compared to low grade prostate cancer [12], two commercial platforms used to predict prognosis (Prolaris from Myriad Genetics and Decipher from GenomeDx Biosciences) [13–16], and a set of transcripts upregulated in a model of castration resistant prostate cancer [17].