These proteins comprised have previously been demonstrated to be present on tumor endothelium and have been used as targets of tumor endothelium vaccination: VEGFR2 [42–45], TEM-1 [46–48], Endoglin [49, 50], ROBO [51], FGF-R2 [5, 52], and EGF-R [53, 54]. This evidence concerns the gene ENG and neoplasm.