De Melo et al. [17] reported deletions of ABL or BCR regions in 21% of Ph-neg CML cases, concluding that the loss of genomic material is an effect of any DNA breakage event at chromosome 9q34 and 22q11 regardless of the mechanism of chromosomal rearrangement. Here, BCR is linked to chronic myelogenous leukemia, BCR-ABL1 positive.